Berberine is an important alkaloid and is a traditional Chinese medicine that has been used for a long time in the world. It can be extracted from plants such as Coptis chinensis , Phellodendron chinense Schneid.cork, and Berberis sargentiana Schneid. It has a remarkable bacteriostatic effect. The commonly used berberine hydrochloride is also called berberine hydrochloride, and its chemical structure is shown in the figure. Berberine can fight against pathogenic microorganisms and inhibit various bacteria such as dysentery bacilli, tuberculosis, pneumococcal bacteria, typhoid bacillus and diphtheria bacilli. Among them, zeosin has the strongest effect and is commonly used to treat bacterial gastroenteritis and dysentery. Equal gastrointestinal disease. It is mainly used for the treatment of bacterial dysentery and gastroenteritis, and it has fewer side effects.